Anavex Life Sciences Stock Plummets on Regulatory Setback for Alzheimer’s Treatment
Anavex Life Sciences (AVXL) shares collapsed 44.6% in premarket trading after European regulators delivered a negative opinion on its experimental Alzheimer's drug blarcamesine. The CHMP's rejection of the Marketing Authorisation Application marks a significant hurdle for the biopharma's lead candidate.
Company executives signaled plans to appeal the decision, citing constructive dialogue during regulatory hearings. "The discussion provided valuable education around our oral blarcamesine program," said R&D head Juan Carlos Lopez-Talavera. The treatment targets early-stage Alzheimer's patients, a population with limited therapeutic options.